In order to assess, monitor and optimally treat noninfectious anterior uveitis, it is crucial to have accurate, consistent and conventional diagnosis of the main disease’s sign: the anterior chamber cells (ACCs).
Tarsier Pharma, in collaboration with Prof. de Smet, Prof. Cunningham, Dr. Neumann, and Dr. Kramer, have developed the Tarsier Grading Image Scale (GIS) to improve ACC grading by slit lamp bio-microscopy. The Tarsier GIS is a visual analog scale that graphically represents a high-power field slit beam through the anterior chamber, from the cornea to the lens surface, to evaluate an anterior uveitic flare-up.
Cells were represented as white dots, dimensioned to represent lymphocytes, and distributed throughout the anterior chamber in an inhomogeneous fashion. The reference images were set at the upper limit of each grade.